Method for preparing anti-tumor nano composite medicine from synergetic streptonigrin

The invention discloses a method for preparing an anti-tumor nano composite medicine from synergetic streptonigrin. The method comprises the following steps: embedding TEMPOL and STN (Streptonigrin) into MSNs, thereby obtaining a nano anti-tumor medicine of which streptonigrin is combined with nitroxide free radicals. The nano material is capable of well containing active molecules of streptonigrin, plays a role in targeting transportation and is capable of reducing toxic and side effects to the maximum extent; meanwhile, the streptonigrin is further detoxified through the nitroxide free radicals; and in addition, lenalidomide molecules are specifically modified to the surfaces of nano molecules and are combined with integrin to carry out target conveying of the composition medicine to tumor cells, and then effects that streptonigrin is efficiently utilized and toxic and side effects of other normal cells are eliminated are achieved. 本发明的种协同链黑菌素制备抗肿瘤纳米组合药物的方法，将TEMPOL与STN起镶嵌在MSNs中形成种由链黑菌素和氮氧自由基组合的纳米抗肿瘤药物，该纳米材料