Method for detecting 1,2-diaminobenzene drugs in animal tissues and dairy products

In view of the fact that 1,2-diaminobenzene anthelmintic drugs may cause teratogenesis and embryotoxicity in animals including humans, the present invention discloses a method for rapid and accurate determination of amounts of residues of 19 kinds of 1,2-diaminobenzene drugs in animal tissues and dairy products. The method of detecting the drug residues is used to ensure food safety, especially health of sensitive groups such as the elderly, pregnant women and infants. The method for determination of the 19 kinds of 1,2-diaminobenzene drugs in the animal tissues and dairy products is established by technologies such as high performance liquid chromatography-tandem quadrupole mass spectrometry combined with electrospray ionization monitoring. The method is simple in operation, high in sensitivity, strong in anti-interference ability, accurate in qualitation and quantitation, can provide a technical support for the monitoring of the 19 kinds of 1,2-diaminobenzene drugs in the animal tissues and dairy products,