Patch system for transdermal absorption with minimized skin irritation

The invention relates to a patch system for transdermal absorption, which comprises: (a) an outer protective layer; (b) a solvent-type adhesive layer; (c) a non-solvent-type adhesive layer; and (d) arelease layer. The release layer is a film that is removed before use. The solvent-type adhesive layer is adjacent to the outer protective layer, and the non-solvent-type adhesive layer is adjacent tothe release layer and is in contact with skin when applied to the skin. The solvent-type adhesive layer and/or the non-solvent-type adhesive layer include one or more components selected from the group consisting of skin active ingredients and pharmaceutically active ingredients. Skin irritation is minimized when the patch system applied to skin of a human body while percutaneous absorption of various active components is efficiently enabled. 本发明涉及种用于经皮吸收的贴剂系统，包括(a)外保护层，(b)溶剂型粘合剂层，(c)非溶剂型粘合剂层，以及(d)释放层，所述释放层为在使用前被去除的膜，其中，所述溶剂型粘合剂层与所述外保护层相邻，并且所述非溶剂型粘合剂层与所述释放层相邻并且在使用时与皮肤接触，以及其中，所述溶剂型粘合剂层和/或所述非溶剂型粘合剂层包括选自由皮肤活性成分和药用活性成分组成的