Medicine for effectively treating complications of central venous catheter and application thereof

The invention belongs to the field of medicines, and particularly relates to a medicine for effectively treating complications of a central venous catheter and application thereof. The medicine is prepared from rhTNK-tPA and polysaccharide sulfate according to the weight ratio of (0.1-0.5):1. Compar...

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Bibliographische Detailangaben
Hauptverfasser: YANG QIN, WANG SEN, CAO JINGWEN, MU GUOHUI, WU YINAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of medicines, and particularly relates to a medicine for effectively treating complications of a central venous catheter and application thereof. The medicine is prepared from rhTNK-tPA and polysaccharide sulfate according to the weight ratio of (0.1-0.5):1. Compared with the prior art, the medicine with a remarkable curative effect on the complications of the central venous catheter has the advantages that an excellent repair effect on a dysfunctional catheter is achieved, after the medicine is injected once, the recanalization rate of the catheter can reach80% or above, the blood flow rate can reach 236 ml/min or above, the maximum blood flow rate can reach 253 ml/min, the rise of the APTT and PT level in peripheral blood cannot be caused, and therefore the risk of clinical bleeding is greatly reduced, no severe adverse reactions is caused, and remarkable progress is made compared with the prior art. 本发明属于医药领域,具体涉及有效治疗中心静脉导管并发症的药物及其用途。所述药物由rhTNK-tPA和藻酸双酯钠按(0.1~0.5):1的重量比组成