Application of polypyrrole nanosphere for preparing medicine capable of preventing and curing Alzheimer disease

The invention discloses application of a polypyrrole nanosphere for preparing a medicine capable of preventing and curing the Alzheimer disease, and belongs to the field of biological medicines. The surface of the polypyrrole nanosphere is modified by polyvinylpyrrolidone, the particle size of the p...

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Hauptverfasser: ZHU CHUNLING, LIU ZEXIU, XIE ZENGHONG, LIN XUCONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses application of a polypyrrole nanosphere for preparing a medicine capable of preventing and curing the Alzheimer disease, and belongs to the field of biological medicines. The surface of the polypyrrole nanosphere is modified by polyvinylpyrrolidone, the particle size of the polypyrrole nanosphere is 40-60 nm, and the polypyrrole nanosphere can be used for inhibiting the activity of A beta protein aggregation and degradation fibrosis A beta protein, has excellent characteristics of easiness in clearing, good biocompatibility, strong photothermal and the like, and can beused as a potential medicine for treating the Alzheimer disease. 本发明公开了种聚吡咯纳米球在制备防治阿尔茨海默病药物中的应用,属于生物医药领域,所述聚吡咯纳米球表面经聚乙烯吡咯烷酮改性,其粒径为40-60nm,具有抑制Aβ蛋白聚集及降解纤维化Aβ蛋白的活性,且其具有易清除、生物相亲性良好、光热强等优异特性,可作为治疗阿尔茨海默病的潜在药物。