Method for producing HPV11 (Human Papillomavirus 11) L1 protein by utilizing hansenula polymorpha expression system

The invention relates to a method for producing HPV11 (Human Papillomavirus 11) L1 protein by utilizing a hansenula polymorpha expression system. Specifically, the invention discloses a method for producing a recombinant hansenula polymorpha cell for expressing the HPV11 L1 protein, and the recombin...

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Hauptverfasser:	LIU JUAN, CHEN DAN, WANG YIJIE, LI DINGFENG, HUO ZHU, BAN JINGYANG, CHENG HAI, LIU YONG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a method for producing HPV11 (Human Papillomavirus 11) L1 protein by utilizing a hansenula polymorpha expression system. Specifically, the invention discloses a method for producing a recombinant hansenula polymorpha cell for expressing the HPV11 L1 protein, and the recombinant hansenula polymorpha cell produced by the method. The invention further discloses a method for producing the HPV11 L1 protein by utilizing the recombinant hansenula polymorpha cell and application of the produced HPV11 L1 protein to preparation of preventive vaccines. 本发明涉及用汉逊酵母表达系统产生HPV11L1蛋白的方法。具体地，本发明公开了产生表达HPV11L1蛋白的重组汉逊酵母细胞的方法以及由所述方法产生的重组汉逊酵母细胞。本发明还公开了利用所述重组汉逊酵母细胞产生HPV11L1蛋白的方法以及所产生的HPV11L1蛋白在制备预防性疫苗中的用途。