COMPOSITION FOR PREVENTING AND TREATING INFLAMMATORY BOWEL DISEASES

The present invention relates to: a composition for preventing, treating or alleviating inflammatory bowel diseases, containing, as an active ingredient, a mixture extract comprising two or more of Aucklandia lappa Decne, Terminalia chebula Retzius and Zingiber officinale Rosc.; and a preparation method therefor and, more specifically, to a pharmaceutical composition, of a mixture extract of Aucklandia lappa Decne, Terminalia chebula Retzius and Zingiber officinale Rosc., having an effect of inhibiting monocyte adhesion in enterocytes, an effect of inhibiting the generation of inflammatory cytokines, an effect of alleviating colitis of a dextran sodium sulfate (DSS)-induced colitis animal model, and an effect of alleviating Crohn's disease of a 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease animal model. 本发明涉及用于预防、治疗或缓解炎性肠病的组合物，所述组合物含有作为活性成分的包含木香、诃子和姜中的两种以上的混合提取物；并涉及其制备方法；更具体而言，涉及木香、诃子和姜的混合提取物的药物组合物，所述药物组合物具有抑制肠上皮细胞中的单核细胞粘附的作用、抑制炎性细胞因子的产生的作用、缓解葡聚糖硫酸钠(DSS)诱导的结肠炎动物模型中的结肠炎的作用以及缓解2,4,6-三硝基苯磺酸(T