Application of o-methylanilinyl lithium to catalysis of ketone and borane to generate hydroboration reaction

The invention relates to application of o-methylanilinyl lithium and particularly relates to efficient application of o-methylanilinyl lithium to catalysis of ketone and borane to generate hydroboration reaction. The application comprises the following processes: under the water-free and oxygen-free environment and in the inert gas atmosphere, adding borane to a reaction flask subjected to dehydration and deoxidization treatment, then adding o-methylanilinyl lithium as a catalyst, performing uniform mixing, then adding ketone to generate hydroboration reaction, and exposing the product to theair to stop the reaction so as to obtain borate, wherein ketone is aliphatic ketone. The catalyst disclosed by the invention has better universality for aliphatic ketones with different structures, thereby providing more options for obtaining borate compounds with different substituent structures. 本发明涉及的邻甲基苯胺基锂的应用，具体涉及邻甲基苯胺基锂在催化酮与硼烷硼氢化反应中的高效应用；无水无氧环境下，惰性气体氛围中，在经过脱水脱氧处理的反应瓶中加入硼烷，然后加入催化剂邻甲基苯胺基锂，混合均匀，再加入酮，发生硼氢化反应，暴露于空气中终止反应，