Azilsartan tablet and preparation method thereof

The invention belongs to the technical field of pharmaceutic preparations, and particularly relates to an azilsartan tablet and a preparation method thereof. The provided azilsartan tablet comprises the following preparation raw materials in percentages by weight: 14-28% of azilsartan, 25-55% of a d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GAO WEI, XU YUN, CONG HAIJIAN, JIANG FENG, YANG RUI
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention belongs to the technical field of pharmaceutic preparations, and particularly relates to an azilsartan tablet and a preparation method thereof. The provided azilsartan tablet comprises the following preparation raw materials in percentages by weight: 14-28% of azilsartan, 25-55% of a diluent (I), 8-26% of a diluent (II), 8-12% of a diluent (III), 1-4% of a stabilizer, 4-8% of a disintegrating agent, 0.4-2% of a lubricating agent and 1-3% of a binding agent. The prepared azilsartan tablet is smooth in appearance, good in hardness, small in tablet weight difference and uniform in content, and in-vitro dissolution behaviors of the azilsartan tablet are consistent to those of original drug. Through acceleration tests for six month, single impurity content is 0.14%, the sum of impurity contents is 0.54%, the quality is excellent, the stability is good, the process is simple, and commercialized production is facilitated. 本发明属于药物制剂技术领域,具体涉及种阿齐沙坦片及其制备方法。本发明提供的阿齐沙坦片包括以下重量百分比计的制备原料:阿齐沙坦14~28%、稀释剂()25~55%、