Celecoxib pharmaceutical composition and preparation method thereof

The invention relates to a celecoxib pharmaceutical composition and a preparation method of the celecoxib pharmaceutical composition and preparation method. More specifically, the invention belongs tothe field of pharmaceutic preparations. The celecoxib pharmaceutical composition comprises a solid dispersing body and optionally comprises pharmaceutically acceptable ingredients and a crystallization inhibitor, the solid dispersing body comprises celecoxib, an insoluble dispersing agent and a biological adhesive material. The pharmaceutical composition is absorbed rapidly after being orally taken, and the effective blood concentration is reached at the low dosage. 本发明涉及塞来昔布药物组合物及其制备方法。具体而言，本发明属于药物制剂领域。本发明的塞来昔布药物组合物包含固体分散体，任选地包含药学上可接受的辅料，所述固体分散体含有塞来昔布、难溶性分散剂和生物粘附材料，任选地包含抑晶剂。所述药物组合物口服吸收快，低剂量就能达到有效血药浓度。