Preparation method of polysaccharide quaternary ammonium salt antibacterial dressing

The invention relates to a preparation method of polysaccharide quaternary ammonium salt antibacterial dressing. The preparation method specifically comprises the following steps: enabling yeast glucan to react with 2-bromoisobutylol bromide to obtain a polysaccharide initiator yg-Br, reacting with glycidyl methacrylate, pentamethyl diethylenetriamine and cuprous bromide to obtain yg-PGMA, performing ring opening with ethanediamine to obtain yg-PGED, reacting with iodomethane to obtain a quaternary ammonium salt polymer antibacterial material Q-yg-PGED, performing heating dissolution, mold pouring and cooling molding treatment on the Q-yg-PGED and re-molding to obtain the antibacterial dressing. The antibacterial dressing has good biocompatibility and can effectively inhibit bacteria growth and kill bacteria adhered onto the surface of a biomedical material. An in-vivo experiment shows that the polysaccharide quaternary ammonium salt antibacterial dressing can significantly treat the staphylococcal infection