Cephem compounds, their production and use
Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic heterocyclic ring as the quaternary ammoniomethyl group at the 3-position and one or both of a terminal amidine residue (substituted or unsubstitut...
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| creator | LING RONG HA CHAN MINH MAITI SAMARENDRA NATH YIP JUDY SHAN RUDONG MADALA MADHAVA REDDY NGUYEN DAI QUOC REDDY ANDHE V N |
| description | Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic heterocyclic ring as the quaternary ammoniomethyl group at the 3-position and one or both of a terminal amidine residue (substituted or unsubstituted) attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) whichis further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain, or a terminal guanidine residue attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) which is further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain.
头孢烯化合物、其药学上可接受的盐及其使用方法，其中所述化合物具有双环含氮芳杂环作为3位的季铵甲基，和以下中的个或两个：连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端脒残基(取代的或未取代的)，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N原子；或连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端胍残基，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N |
| format | Patent |
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头孢烯化合物、其药学上可接受的盐及其使用方法，其中所述化合物具有双环含氮芳杂环作为3位的季铵甲基，和以下中的个或两个：连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端脒残基(取代的或未取代的)，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N原子；或连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端胍残基，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N</description><language>chi ; eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180828&DB=EPODOC&CC=CN&NR=108463461A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180828&DB=EPODOC&CC=CN&NR=108463461A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LING RONG</creatorcontrib><creatorcontrib>HA CHAN MINH</creatorcontrib><creatorcontrib>MAITI SAMARENDRA NATH</creatorcontrib><creatorcontrib>YIP JUDY</creatorcontrib><creatorcontrib>SHAN RUDONG</creatorcontrib><creatorcontrib>MADALA MADHAVA REDDY</creatorcontrib><creatorcontrib>NGUYEN DAI QUOC</creatorcontrib><creatorcontrib>REDDY ANDHE V N</creatorcontrib><title>Cephem compounds, their production and use</title><description>Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic heterocyclic ring as the quaternary ammoniomethyl group at the 3-position and one or both of a terminal amidine residue (substituted or unsubstituted) attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) whichis further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain, or a terminal guanidine residue attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) which is further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain.
头孢烯化合物、其药学上可接受的盐及其使用方法，其中所述化合物具有双环含氮芳杂环作为3位的季铵甲基，和以下中的个或两个：连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端脒残基(取代的或未取代的)，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N原子；或连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端胍残基，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNByTi3ISM1VSM7PLcgvzUsp1lEoyUjNLFIoKMpPKU0uyczPU0jMS1EoLU7lYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GBhYmZsYmZoaOxsSoAQAlVSjs</recordid><startdate>20180828</startdate><enddate>20180828</enddate><creator>LING RONG</creator><creator>HA CHAN MINH</creator><creator>MAITI SAMARENDRA NATH</creator><creator>YIP JUDY</creator><creator>SHAN RUDONG</creator><creator>MADALA MADHAVA REDDY</creator><creator>NGUYEN DAI QUOC</creator><creator>REDDY ANDHE V N</creator><scope>EVB</scope></search><sort><creationdate>20180828</creationdate><title>Cephem compounds, their production and use</title><author>LING RONG ; HA CHAN MINH ; MAITI SAMARENDRA NATH ; YIP JUDY ; SHAN RUDONG ; MADALA MADHAVA REDDY ; NGUYEN DAI QUOC ; REDDY ANDHE V N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN108463461A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2018</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LING RONG</creatorcontrib><creatorcontrib>HA CHAN MINH</creatorcontrib><creatorcontrib>MAITI SAMARENDRA NATH</creatorcontrib><creatorcontrib>YIP JUDY</creatorcontrib><creatorcontrib>SHAN RUDONG</creatorcontrib><creatorcontrib>MADALA MADHAVA REDDY</creatorcontrib><creatorcontrib>NGUYEN DAI QUOC</creatorcontrib><creatorcontrib>REDDY ANDHE V N</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LING RONG</au><au>HA CHAN MINH</au><au>MAITI SAMARENDRA NATH</au><au>YIP JUDY</au><au>SHAN RUDONG</au><au>MADALA MADHAVA REDDY</au><au>NGUYEN DAI QUOC</au><au>REDDY ANDHE V N</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cephem compounds, their production and use</title><date>2018-08-28</date><risdate>2018</risdate><abstract>Cephem compounds, pharmaceutically acceptable salts thereof, and methods of using same, wherein the compound has a bicyclic nitrogen-containing aromatic heterocyclic ring as the quaternary ammoniomethyl group at the 3-position and one or both of a terminal amidine residue (substituted or unsubstituted) attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) whichis further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain, or a terminal guanidine residue attached to an aryl or a 5- or 6- membered heteroaryl group (substituted or unsubstituted) which is further attached through a spacer to the free N-atom of the quaternary nitrogen-containing bicyclic ring at the 3-side chain.
头孢烯化合物、其药学上可接受的盐及其使用方法，其中所述化合物具有双环含氮芳杂环作为3位的季铵甲基，和以下中的个或两个：连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端脒残基(取代的或未取代的)，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N原子；或连接到芳基或5-或6-元杂芳基(取代的或未取代的)的末端胍残基，所述芳基或5-或6-元杂芳基(取代的或未取代的)还通过间隔基团连接到3-侧链上的含季氮的双环的游离N</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Cephem compounds, their production and use |
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