Applications of niclosamide ethanolamine salt and medicinal composition thereof

The invention relates to applications of niclosamide ethanolamine salt and a medicinal composition of the niclosamide ethanolamine salt. After the niclosamide ethanolamine salt and the medicinal composition of the niclosamide ethanolamine salt are applied, an uncoupling effect can be achieved on the kidney tissue mitochondria, the excretion of proteinuria of mice with kidney diseases can be reduced, the glomerular sclerosis and renal tubular injuries can be improved, the level of serum creatinine can be reduced, and therefore, the niclosamide ethanolamine salt and medicinal composition of theniclosamide ethanolamine salt have a certain protection effect for the kidney diseases, and can be used for preventing and treating the kidney diseases. 本发明涉及种氯硝柳胺乙醇胺盐及其药物组合物的应用，其可对肾组织线粒体起到解偶联作用，减少肾病小鼠的蛋白尿排泄，改善肾小球硬化和肾小管损伤，降低血清肌酐水平，因此氯硝柳胺乙醇胺盐及其药物组合物对肾脏疾病具有定的保护作用，可以用于预防和治疗肾脏疾病。