Method used for increasing terramycin yield based on afsQ1Q2-like double-component adjusting system

The invention relates to a method used for increasing terramycin yield based on an afsQ1Q2-like double-component adjusting system. In the invention, the close relationship of the afsQ1Q2-like double-component adjusting system in producing strains with terramycin yield of the producing strains is disclosed for the first time; down regulation of the afsQ1Q2-like double-component adjusting system, and taking glycine or aspartic acid as the only nitrogen source in culture are capable of increasing the terramycin yield of the producing strains significantly. The afsQ1Q2-like double-component adjusting system or substances or methods used for adjusting the afsQ1Q2-like double-component adjusting system can be used in modification of terramycin producing strains, and increasing of terramycin yield. 本发明涉及基于afsQ1Q2-like双组分调节系统提高土霉素产量的方法。本发明首次提出土霉素生产菌中afsQ1Q2-like双组分调节系统与该生产菌的土霉素产量密切相关，下调该双组分调节系统，并且在培养时以甘氨酸或天冬氨酸为唯氮源，可以极为显著地提高土霉素生产菌的土霉素产量。因此，afsQ1Q2-like双组分调节系统或调节该系统的物质和方法可应用于实现土霉素生产菌的改良，增强土霉素的产量。