QUICK DISSOLVING DIPHENHYDRAMINE ORAL DOSAGE FORM
An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeabilityenhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The...
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Zusammenfassung: | An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeabilityenhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The diphenhydramine can completely dissolve within about 2 minutes.
本发明提供了种通过舌下或颊面黏膜递送苯海拉明的口服剂型。所述口服剂型可包含苯海拉明、或其药学上可接受的盐、渗透增强剂和缓冲剂。所述缓冲剂可达到约7.0至约8.0的pH。苯海拉明可在约2分钟内完全溶解。 |
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