Method for detecting organic solvent residues in liposome for injection

The invention relates to a method for detecting organic solvent residues in liposome for injection. The method utilizes a gas chromatography detection method, eliminates interference of a complex matrix environment by a standard addition method, accurately determines methanol, ethanol and chloroform...

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Bibliographische Detailangaben
Hauptverfasser: SONG QING, ZHONG SHAOPENG, TONG SHUWEN, LIU JINJIE, LU DI, ZHAO YANPING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a method for detecting organic solvent residues in liposome for injection. The method utilizes a gas chromatography detection method, eliminates interference of a complex matrix environment by a standard addition method, accurately determines methanol, ethanol and chloroform contents, and has high sensitivity, good repeatability and high accuracy. 本发明为种注射用脂质体中有机溶剂残留的检测方法,采用气相色谱检测方法,同时用标准加入的方式消除复杂基质环境的干扰,准确测定甲醇、乙醇和三氯甲烷含量,灵敏度高,重复性好,准确度高。