Xanthoceras-sorbifolia-bunge seed shell extract and application of xanthoceras-sorbifolia-bunge seed shell extract to medicine for treating and/or preventing multiple sclerosis

The invention discloses a preparing method for xanthoceras-sorbifolia-bunge seed shell extract. The preparing method includes the steps that xanthoceras-sorbifolia-bunge seed shells are extracted witha methanol water solution, then hydrochloric acid is added, acidizing and filtering are carried out,...

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Bibliographische Detailangaben
Hauptverfasser: LI XING, ZHAO LI, ZHANG YUAN, HAN JUANJUAN, YE ZEQING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a preparing method for xanthoceras-sorbifolia-bunge seed shell extract. The preparing method includes the steps that xanthoceras-sorbifolia-bunge seed shells are extracted witha methanol water solution, then hydrochloric acid is added, acidizing and filtering are carried out, extraction is carried out with ethyl acetate, evaporation is carried out under pressure reduction,and the xanthoceras-sorbifolia-bunge seed shell extract is obtained. Constitutes and the content are measured through GC-MS after silylation derivatization, the xanthoceras-sorbifolia-bunge seed shell extract comprises 20 phenolic compounds, and the 20 phenolic compounds account for 84.62% of the xanthoceras-sorbifolia-bunge seed shell extract; main components comprise 20.05% of caffeic acid, 9.32% of p-hydroxyphenylacetic acid, 8.84% of p-coumaric acid and 8.29% of trans-o-coumaric acid. Whole animal model experimental research shows that the xanthoceras-sorbifolia-bunge seed shell extract has the remarkable improvem