Method for preparing drug balloon
The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum dryin...
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| creator | CAO MINGFANG SONG JINGZHONG XIE QIZONG |
| description | The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum drying treatment on the balloon after the low-temperature freezing treatment to obtain the drug balloon;the temperature of the low-temperature freezing treatment is not higher than a freezing point of the solvent, and the temperature of the vacuum drying treatment is lower than the freezing point of thesolvent, and is lower than glass state temperature of the polymer. According to the method for preparing the drug balloon, a uniform porous structure is formed on the surface of the balloon, the drugis uniformly distributed in the porous structure, so that the specific surface area of drug particles can be increased, and the drug can fully contact sites of target cells when the balloon is expanded, and is uniformly releas |
| format | Patent |
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The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum drying treatment on the balloon after the low-temperature freezing treatment to obtain the drug balloon;the temperature of the low-temperature freezing treatment is not higher than a freezing point of the solvent, and the temperature of the vacuum drying treatment is lower than the freezing point of thesolvent, and is lower than glass state temperature of the polymer. According to the method for preparing the drug balloon, a uniform porous structure is formed on the surface of the balloon, the drugis uniformly distributed in the porous structure, so that the specific surface area of drug particles can be increased, and the drug can fully contact sites of target cells when the balloon is expanded, and is uniformly releas</description><language>chi ; eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180710&DB=EPODOC&CC=CN&NR=108261569A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180710&DB=EPODOC&CC=CN&NR=108261569A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAO MINGFANG</creatorcontrib><creatorcontrib>SONG JINGZHONG</creatorcontrib><creatorcontrib>XIE QIZONG</creatorcontrib><title>Method for preparing drug balloon</title><description>The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum drying treatment on the balloon after the low-temperature freezing treatment to obtain the drug balloon;the temperature of the low-temperature freezing treatment is not higher than a freezing point of the solvent, and the temperature of the vacuum drying treatment is lower than the freezing point of thesolvent, and is lower than glass state temperature of the polymer. According to the method for preparing the drug balloon, a uniform porous structure is formed on the surface of the balloon, the drugis uniformly distributed in the porous structure, so that the specific surface area of drug particles can be increased, and the drug can fully contact sites of target cells when the balloon is expanded, and is uniformly releas</description><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD0TS3JyE9RSMsvUigoSi1ILMrMS1dIKSpNV0hKzMnJz8_jYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GBhZGZoamZpaOxsSoAQB6YiWd</recordid><startdate>20180710</startdate><enddate>20180710</enddate><creator>CAO MINGFANG</creator><creator>SONG JINGZHONG</creator><creator>XIE QIZONG</creator><scope>EVB</scope></search><sort><creationdate>20180710</creationdate><title>Method for preparing drug balloon</title><author>CAO MINGFANG ; SONG JINGZHONG ; XIE QIZONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN108261569A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2018</creationdate><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><toplevel>online_resources</toplevel><creatorcontrib>CAO MINGFANG</creatorcontrib><creatorcontrib>SONG JINGZHONG</creatorcontrib><creatorcontrib>XIE QIZONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAO MINGFANG</au><au>SONG JINGZHONG</au><au>XIE QIZONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method for preparing drug balloon</title><date>2018-07-10</date><risdate>2018</risdate><abstract>The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum drying treatment on the balloon after the low-temperature freezing treatment to obtain the drug balloon;the temperature of the low-temperature freezing treatment is not higher than a freezing point of the solvent, and the temperature of the vacuum drying treatment is lower than the freezing point of thesolvent, and is lower than glass state temperature of the polymer. According to the method for preparing the drug balloon, a uniform porous structure is formed on the surface of the balloon, the drugis uniformly distributed in the porous structure, so that the specific surface area of drug particles can be increased, and the drug can fully contact sites of target cells when the balloon is expanded, and is uniformly releas</abstract><oa>free_for_read</oa></addata></record> |
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| language | chi ; eng |
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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL |
| title | Method for preparing drug balloon |
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