Method for preparing drug balloon

The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum dryin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CAO MINGFANG, SONG JINGZHONG, XIE QIZONG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to a method for preparing a drug balloon. The method comprises the steps of uniformly applying a mixed solution containing a drug, a polymer and a solvent onto the surface of a balloon; conducting low-temperature freezing treatment on the coated balloon; conducting vacuum drying treatment on the balloon after the low-temperature freezing treatment to obtain the drug balloon;the temperature of the low-temperature freezing treatment is not higher than a freezing point of the solvent, and the temperature of the vacuum drying treatment is lower than the freezing point of thesolvent, and is lower than glass state temperature of the polymer. According to the method for preparing the drug balloon, a uniform porous structure is formed on the surface of the balloon, the drugis uniformly distributed in the porous structure, so that the specific surface area of drug particles can be increased, and the drug can fully contact sites of target cells when the balloon is expanded, and is uniformly releas