Preparation method of 2, 3-difluorophenylethyl ether

The invention relates to a preparation method of 2, 3-difluorophenylethyl ether. The preparation method comprises the following steps: (1), performing a diazo reaction: taking 6-amino-2, 3-difluorophenylethyl ether as a raw material, forming salt in acid, and performing the diazo reaction with sodiu...

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Hauptverfasser: LIU FENG, PAN ZHIJUN, WANG DILIANG, JIN NINGREN, LIU JINFENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method of 2, 3-difluorophenylethyl ether. The preparation method comprises the following steps: (1), performing a diazo reaction: taking 6-amino-2, 3-difluorophenylethyl ether as a raw material, forming salt in acid, and performing the diazo reaction with sodium nitrite to obtain a reaction solution; (2), deaminating: dropwise adding the reaction solution into catalyst-containing ethanol, filtering, standing for layering, and concentrating to obtain crude 2, 3-difluorophenylethyl ether; (3), purifying: performing reduced pressure distillation on the crude2, 3-difluorophenylethyl ether to obtain refined 2, 3-difluorophenylethyl ether. According to the preparation method, a technology is simple, the product posttreatment is simple and convenient, the environment pollution is small, and the prepared 2, 3-difluorophenylethyl ether has high product quality; the environment pollution is reduced while the product quality is improved, so that product production is clean and envi