Tilmicosin inclusion compound and preparation method thereof

The invention discloses a tilmicosin inclusion compound and a preparation method thereof. The tilmicosin inclusion compound is prepared from the following raw materials in percentage by weight: 20-50parts of tilmicosin, 5-20 parts of a macromolecule carrier, 0.5-2 parts of a disintegrating agent, 30-60 parts of an adhesive and 1-6 parts of an inclusion material. Compared with the prior art, the tilmicosin inclusion compound is prepared from polyethylene glycol as a carrier, tilmicosin is included by ethyecellulose, then the bitterness of the tilmicosin can be well covered, the tilmicosin inclusion compound is simple and convenient to operate, and in addition, the prepared tilmicosin has a slow release function. 本发明公开了种替米考星包合物及其制备方法，由以下重量百分比的原料制成：替米考星20-50份，高分子载体5-20份，崩解剂0.5-2份，粘合剂30-60份，包衣材料1-6份。相对于现有技术，本发明以聚乙二醇为载体，利用乙基纤维素将替米考星包被，很好的掩盖了其苦味，操作简便，并且所得替米考星有缓释作用。