Medical preparation containing N6-hydrazinylidene-8-aza-purine compound applicable to oral medication
The invention relates to a medical preparation containing an N6-hydrazinylidene-8-aza-purine compound applicable to oral medication, and belongs to the field of medical preparations. The medical preparation is prepared from, by weight, 10-55 wt% of medicament, 20-50 wt% of water-soluble filler, 10-4...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a medical preparation containing an N6-hydrazinylidene-8-aza-purine compound applicable to oral medication, and belongs to the field of medical preparations. The medical preparation is prepared from, by weight, 10-55 wt% of medicament, 20-50 wt% of water-soluble filler, 10-45 wt% of water-insoluble filler, 2-10 wt% of disintegrant, 2-6 wt% of adhesive and 0.5-2 wt% of lubricant, wherein the water-soluble filler, the water-insoluble filler, the disintegrant, the adhesive and the lubricant are auxiliary materials. The medical preparation containing the N6-hydrazinylidene-8-aza-purine compound applicable to the oral medication is good in compressibility and uniform and stable in product quality, and meets the specification in terms of friability and disintegration time.
包含N-腙基-8-氮杂嘌呤类化合物的适用于口服给药的医药制剂,属于药物制剂领域,所述药剂重量百分含量为10-55wt%。其它辅料重量百分含量水溶性填充剂为20-50wt%、水不溶性填充剂10-45wt%、崩解剂2-10wt%、粘合剂2-6wt%、润滑剂0.5-2wt%。所述产品可压性好,脆碎度和崩解时限符合规定,产品质量均稳定。 |
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