Composition for treatment of inflammatory bowel disease and atopic dermatitis

The present invention relates to a compound for inhibiting the secretion of thymic stromal lymphopoietin (TSLP) from mast cells, and a use thereof. It has been confirmed that the compound of the present invention significantly inhibits the secretion of TSLP from mast cells, and thus the compound can...

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Bibliographische Detailangaben
1. Verfasser:	KANG INOL
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
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Beschreibung
Zusammenfassung:	The present invention relates to a compound for inhibiting the secretion of thymic stromal lymphopoietin (TSLP) from mast cells, and a use thereof. It has been confirmed that the compound of the present invention significantly inhibits the secretion of TSLP from mast cells, and thus the compound can be used as a candidate material for the treatment and prevention of atopic dermatitis, allergic dermatitis and/or inflammatory bowel disease. 本发明涉及抑制肥大细胞的胸腺基质淋巴细胞生成素(TSLP)分泌的化合物，及其用途。确证本发明化合物显著抑制肥大细胞的TSLP分泌，并因此可用作治疗和预防异位性皮炎、变应性皮炎和/或炎性肠病的候选化合物。