NUCLEIC ACID ANALYSIS BY JOINING BARCODED POLYNUCLEOTIDE PROBES

Disclosed are compositions, methods and kits for determining the presence, absence, amount, copy number, or other characteristics of one or more polynucleotide sequences in two or more samples and usethereof in genotyping, evaluation of copy number variation, expression analysis, determination of sp...

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Bibliographische Detailangaben
Hauptverfasser:	MCCOY ADAM, DICKINSON PHILIP H, O'CALLAHAN ROBERT, CURRY JOHN D, FITZPATRICK DANIEL, KOSHINSKY HEATHER, SCHWEITZER ANTHONY C
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed are compositions, methods and kits for determining the presence, absence, amount, copy number, or other characteristics of one or more polynucleotide sequences in two or more samples and usethereof in genotyping, evaluation of copy number variation, expression analysis, determination of splice variants and fusion genes, and other genetic analyses. 本发明公开了用于测定两个或更多个样品中的种或多种多核苷酸序列的存在、不存在、含量、拷贝数或其它特性的组合物、方法和试剂盒，以及所述组合物、方法和试剂盒在基因分型、拷贝数变异的评估、表达分析、剪接变异体和融合基因的测定及其它遗传分析中的应用。