GITRL FUSION PROTEINS AND USES THEREOF

The disclosure provides GITRL fusion polypeptide subunits comprising an IgG Fc domain, a trimerization domain, and the receptor binding domain of GITR ligand, where the fusion polypeptide subunits canself-assemble into hexameric proteins. Also provided are methods of making fusion polypeptide subuni...

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Hauptverfasser: STEWART ROSS ANTHONY, YOUNG LESLEY LYNN, TIGUE NATALIE JO, HIGAZI DANIEL RAMSAY, DURHAM NICHOLAS MASON, LEYLAND REBECCA, SRIDHARAN SUDHARSAN, BAMBER LISA
Format: Patent
Sprache:chi ; eng
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