Method for preparing erivedge by adopting microchannel reaction device

The invention discloses a method for preparing erivedge by adopting a microchannel reaction device. The method comprises the following steps: by using 2-phenylpyridine as a starting material, preparing an important intermediate 4-chloro-3-(pyridine-2-yl) aniline by metal catalysis amination, oxidation and reduction reaction in sequence, finally carrying out oxidation and amidation reaction with 2-chloro-1-methyl-4-(methylsulfonyl)benzene by two-step continuous flow in the novel microchannel reaction device, and preparing the erivedge. The microchannel reaction device has the characteristics ofcheap price, convenience in transportation and cleaning, higher heat and mass transfer efficiency and easier industrial amplification and the like. Compared with the prior art, the synthesis method has the advantages that the starting material is simple and cheap and is easy to obtain, the process is concise, the production cost can be effectively reduced, and the adaptability to industrial production is achieved. 本发明公开种