SACUBITRIL CALCIUM SALTS
The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful i...
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| creator | WAYKOLE LILADHAR MURLIDHAR SUTTON PAUL ALLEN KLEINBECK FLORIAN KARL WIETFELD BERNHARD MEIER ULRICH HOOK DAVID MUTZ JEAN-PAUL MUELLER SIBYLLE SCHLOMACH JAN HU BIN |
| description | The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.
本发明涉及N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯钙盐的多晶型。N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯的钙盐用于治疗响应中性内肽酶抑制的多种病症和紊乱。 |
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本发明涉及N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯钙盐的多晶型。N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯的钙盐用于治疗响应中性内肽酶抑制的多种病症和紊乱。</description><language>chi ; eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2018</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180501&DB=EPODOC&CC=CN&NR=107980038A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180501&DB=EPODOC&CC=CN&NR=107980038A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WAYKOLE LILADHAR MURLIDHAR</creatorcontrib><creatorcontrib>SUTTON PAUL ALLEN</creatorcontrib><creatorcontrib>KLEINBECK FLORIAN KARL</creatorcontrib><creatorcontrib>WIETFELD BERNHARD</creatorcontrib><creatorcontrib>MEIER ULRICH</creatorcontrib><creatorcontrib>HOOK DAVID</creatorcontrib><creatorcontrib>MUTZ JEAN-PAUL</creatorcontrib><creatorcontrib>MUELLER SIBYLLE</creatorcontrib><creatorcontrib>SCHLOMACH JAN</creatorcontrib><creatorcontrib>HU BIN</creatorcontrib><title>SACUBITRIL CALCIUM SALTS</title><description>The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.
本发明涉及N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯钙盐的多晶型。N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯的钙盐用于治疗响应中性内肽酶抑制的多种病症和紊乱。</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2018</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAIdnQOdfIMCfL0UXB29HH2DPVVCHb0CQnmYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxzn6GBuaWFgYGxhaOxsSoAQD18B--</recordid><startdate>20180501</startdate><enddate>20180501</enddate><creator>WAYKOLE LILADHAR MURLIDHAR</creator><creator>SUTTON PAUL ALLEN</creator><creator>KLEINBECK FLORIAN KARL</creator><creator>WIETFELD BERNHARD</creator><creator>MEIER ULRICH</creator><creator>HOOK DAVID</creator><creator>MUTZ JEAN-PAUL</creator><creator>MUELLER SIBYLLE</creator><creator>SCHLOMACH JAN</creator><creator>HU BIN</creator><scope>EVB</scope></search><sort><creationdate>20180501</creationdate><title>SACUBITRIL CALCIUM SALTS</title><author>WAYKOLE LILADHAR MURLIDHAR ; SUTTON PAUL ALLEN ; KLEINBECK FLORIAN KARL ; WIETFELD BERNHARD ; MEIER ULRICH ; HOOK DAVID ; MUTZ JEAN-PAUL ; MUELLER SIBYLLE ; SCHLOMACH JAN ; HU BIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN107980038A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2018</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>WAYKOLE LILADHAR MURLIDHAR</creatorcontrib><creatorcontrib>SUTTON PAUL ALLEN</creatorcontrib><creatorcontrib>KLEINBECK FLORIAN KARL</creatorcontrib><creatorcontrib>WIETFELD BERNHARD</creatorcontrib><creatorcontrib>MEIER ULRICH</creatorcontrib><creatorcontrib>HOOK DAVID</creatorcontrib><creatorcontrib>MUTZ JEAN-PAUL</creatorcontrib><creatorcontrib>MUELLER SIBYLLE</creatorcontrib><creatorcontrib>SCHLOMACH JAN</creatorcontrib><creatorcontrib>HU BIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WAYKOLE LILADHAR MURLIDHAR</au><au>SUTTON PAUL ALLEN</au><au>KLEINBECK FLORIAN KARL</au><au>WIETFELD BERNHARD</au><au>MEIER ULRICH</au><au>HOOK DAVID</au><au>MUTZ JEAN-PAUL</au><au>MUELLER SIBYLLE</au><au>SCHLOMACH JAN</au><au>HU BIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SACUBITRIL CALCIUM SALTS</title><date>2018-05-01</date><risdate>2018</risdate><abstract>The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases.
本发明涉及N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯钙盐的多晶型。N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯的钙盐用于治疗响应中性内肽酶抑制的多种病症和紊乱。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SACUBITRIL CALCIUM SALTS |
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