SACUBITRIL CALCIUM SALTS

The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful i...

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Bibliographische Detailangaben
Hauptverfasser:	WAYKOLE LILADHAR MURLIDHAR, SUTTON PAUL ALLEN, KLEINBECK FLORIAN KARL, WIETFELD BERNHARD, MEIER ULRICH, HOOK DAVID, MUTZ JEAN-PAUL, MUELLER SIBYLLE, SCHLOMACH JAN, HU BIN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to polymorphic forms of the calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester. The calcium salt of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester is useful in the treatment of various conditions and disorders responsive to the inhibition of neutral endopeptidases. 本发明涉及N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯钙盐的多晶型。N-(3-羧基-1-氧丙基)-(4S)-(对苯基苯基甲基)-4-氨基-(2R)-甲基丁酸乙酯的钙盐用于治疗响应中性内肽酶抑制的多种病症和紊乱。