Fermentation production and post-treatment of glutamic acid

The invention provides a method for producing L-glutamic acid through fermentation. The method comprises the following steps: modifying a gene encoded with DNA (Deoxyribonucleic Acid) methylase on a corynebacterium bacterial chromosome to reduce the activity and/or expression amount of the DNA methy...

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Bibliographische Detailangaben
Hauptverfasser:	HA ZHIRUI, ZHAO ERHONG, MA JIYIN, MA WENYOU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FERTILISERS FERTILISERS CHARACTERISED BY THEIR FORM FODDER FOODS OR FOODSTUFFS HUMAN NECESSITIES MANUFACTURE THEREOF METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MIXTURES OF FERTILISERS COVERED INDIVIDUALLY BY DIFFERENTSUBCLASSES OF CLASS C05 MIXTURES OF ONE OR MORE FERTILISERS WITH MATERIALS NOT HAVINGA SPECIFIC FERTILISING ACTIVITY, e.g. PESTICIDES,SOIL-CONDITIONERS, WETTING AGENTS MUTATION OR GENETIC ENGINEERING PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a method for producing L-glutamic acid through fermentation. The method comprises the following steps: modifying a gene encoded with DNA (Deoxyribonucleic Acid) methylase on a corynebacterium bacterial chromosome to reduce the activity and/or expression amount of the DNA methylase; fermenting the modified bacteria to produce the L-glutamic acid. Furthermore, the invention further provides a treatment method of a glutamic acid fermentation solution. 本发明提供了发酵生产L-谷氨酸的方法，其包括改造棒杆菌属细菌染色体上编码DNA甲基化酶的基因，使DNA甲基化酶的活性和/或表达量降低；和，用改造而得到的细菌发酵生产L-谷氨酸。另外，本发明还提供了谷氨酸发酵液的处理方法。