Method for synthesizing S-(4-methylbenzyl)lauryl acid thioester online through lipase catalysis

The invention discloses a method for synthesizing S-(4-methylbenzyl)lauryl acid thioester online through lipase catalysis. Dimethyl sulfoxide is taken as a reaction solvent, 4-methylbenzyl mercaptan and vinyl laurate with the molar ratio of 1: 0.5-6 are taken as raw materials, lipase Lipozyme TL IM is taken as a catalyst, the raw materials and the reaction solvent are placed in an injector, a reaction channel of a micro-fluidic channel reactor is evenly filled with the lipase Lipozyme TL IM, through pushing of an injection pump, the raw materials and the reaction solvent are continuously aerated into the channel reactor for acylation reaction, the inner diameter of the reaction channel of the micro-fluidic channel reactor is 0.8-2.4 mm, and the length of the reaction channel is 0.5-1.0 m;the acylation reaction temperature is controlled at 20-60 DEG C, acylation reaction time is controlled in 20-40 min, through a product collector, reaction liquid is collected online, and after conventional after-treatment is