Fat-soluble photosensitizer, and preparation method and application thereof

The invention discloses a fat-soluble photosensitizer, and a preparation method and application thereof. According to the invention, vitamin E derivatives and inorganic salts of the derivatives are combined with a photosensitizer for treating skin tumors, and skin collagen fibers can be repaired with the help of the protective effect of the vitamin E on healthy skins while tumor cells can be effectively killed, so that the side effects of medicines are greatly reduced. According to the fat-soluble photosensitizer disclosed by the invention, the drug metabolism rate is slowed, so that the drugeffect is more durable. The photosensitizer containing the vitamin E derivatives can generate more free radicals, so that the tumor cells can be killed more efficiently and quickly. The required dosage is far lower than a required dosage of 5-ALA used in the market, antibiotics are not contained, drug resistance is not generated, and the photosensitizer is safe, non-toxic, economical and practical. 本发明公开了种脂溶性光敏剂及其制备方法和应用。