Preparation method of spherical formula granules and related product

The invention relates to a preparation method of spherical formula granules and a related product. The spherical formula granule is an intermediate of a Chinese patent medicine, and has a good moisture-proof function. The preparation method comprises the following steps: (1) preparing extract, namel...

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Hauptverfasser: WANG PING, DONG HAI'OU, YAN XIJUN, ZHU YONGHONG, LIU BING, CHEN CHONG, SUN XIAOBING, YANG JIANHUI, REN QIANG, JU WEI, ZHANG YONGJIE, ZHANG SHUNNAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method of spherical formula granules and a related product. The spherical formula granule is an intermediate of a Chinese patent medicine, and has a good moisture-proof function. The preparation method comprises the following steps: (1) preparing extract, namely extracting traditional Chinese medicine decoction, centrifuging to remove impurities, and concentrating the centrifugate to form the extract containing moderate moisture; (2) preparing an extract and auxiliary material mixture, namely mixing the extract and auxiliary materials, heating, homogenizing, and filtering so as to prepare a mixture with excellent surface compatibility; and (3) preparing microspheres, namely dropping or spraying the mixture prepared in the step (2) into a cold well byvirtue of high-frequency oscillation equipment or pressure atomization equipment, forming semisolid microspheres with certain granularity, passing through a cold well environment at an appropriate temperature in a certain dis