Method for detecting pulmonary embolism

The invention discloses a method for detecting pulmonary embolism. Absolute counting of platelet microparticles in blood plasma is detected to serve as auxiliary diagnosis of the pulmonary embolism bythe method based on standard flow cytometry. Through ROC curve analysis, the critical value of the p...

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Bibliographische Detailangaben
Hauptverfasser: XU LAN, YUE YONGJIAN, LIU SHENGGUO, FU YINGYUN, HUANG QIJUN, WANG MINLIAN, XIAO LU, LI SHULIN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a method for detecting pulmonary embolism. Absolute counting of platelet microparticles in blood plasma is detected to serve as auxiliary diagnosis of the pulmonary embolism bythe method based on standard flow cytometry. Through ROC curve analysis, the critical value of the platelet microparticles for diagnosing the pulmonary embolism is 716.90 per mu l; the sensitivity and the specificity at the critical value are respectively 58.82 percent and 95.92 percent. The positive likelihood ratio is 14.41, and the negative likelihood ratio is 0.43. The positive predictive value is 93.75 percent, and the negative predictive value is 69.12 percent; the Youden's index is 54.74 percent. The method is a non-invasive operation and is low in cost, easy to perform and high in specificity, and can further screen patients with a positive D-dimer result clinically, improves diagnostic specificity, and can serve as an evaluation means before CTPA examination is performed on a patient with the pulmonary e