Thiomatrine derivative as well as preparation method and application thereof

The invention discloses a thiomatrine derivative which comprises pyrrole, quinoline, benzene ring, thiophene, furan, imidazole, pyridine and a naphthalene ring type thiomatrine derivative. The invention further discloses a preparation method and the application of the derivative to anti-tumor. 本发明公开...

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Hauptverfasser: WANG LISHENG, LI ZHENG, JIANG JUN, WU LICHUAN, XIE PENG, LUO MENGYANG, LIU XU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a thiomatrine derivative which comprises pyrrole, quinoline, benzene ring, thiophene, furan, imidazole, pyridine and a naphthalene ring type thiomatrine derivative. The invention further discloses a preparation method and the application of the derivative to anti-tumor. 本发明公开了种硫代苦参碱衍生物,包括吡咯、喹啉、苯环、噻吩、呋喃、咪唑、吡啶、萘环类硫代苦参碱衍生物,还公开了该衍生物的制备方法和在抗肿瘤中的应用。