Detection kit for acute kidney injury

The invention relates to a detection kit for acute kidney injury. The detection kit comprises a first detection solution and a second detection solution, wherein the first detection solution containsa first anti-NGAL monoclonal antibody coated with magnetic particles, and the second detection soluti...

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Bibliographische Detailangaben
Hauptverfasser: YOU MEIXIANG, ZHAO CUNYANG, CHI LANGSHAN, DING ZHENGHUI, LI RUIJING, HU JINLING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a detection kit for acute kidney injury. The detection kit comprises a first detection solution and a second detection solution, wherein the first detection solution containsa first anti-NGAL monoclonal antibody coated with magnetic particles, and the second detection solution contains an alkaline phosphatase-labeled second anti-NGAL monoclonal antibody. The first anti-NGAL monoclonal antibody and the second anti-NGAL monoclonal antibody are against different NGAL epitopes, respectively. The detection kit for acute kidney injury carries out detection with NGAL (neutrophil gelatinase-associated lipocalin) as a diagnosis and detection marker, can rapidly detect and diagnose acute kidney injury in an early stage of acute kidney injury, and has high sensitivity and specificity during detection. 本发明涉及种急性肾损伤的检测试剂盒,包括第检测液和第二检测液,第检测液中含有磁微粒包被的第抗NGAL单克隆抗体,第二检测液中含有碱性磷酸酶标记的第二抗NGAL单克隆抗体。第抗NGAL单克隆抗体和第二抗NGAL单克隆抗体分别针对不同的NGAL表位。该急性肾损伤的检测试剂盒基于NGAL(中性粒细胞明胶酶相关载脂蛋白)作为诊断检测的标志物进行检测,能够在急性肾损伤发生的早期快速检测诊断,检测的灵敏