Oral levetiracetam solution and preparation method thereof

The invention discloses an oral levetiracetam solution and a preparation method thereof and relates to the field of medicine. The oral levetiracetam solution mainly contains levetiracetam, glucosyl-beta-cyclodextrin, a sweetening agent, a preservative, aromatic, buffer salt, a pH regulator and a sol...

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Bibliographische Detailangaben
Hauptverfasser: REN XIA, WU XUEYING, YU LIHUA, ZHAO GANG, WU JINGANG, FANG HUBIAO, HUANG ZHIJUN
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses an oral levetiracetam solution and a preparation method thereof and relates to the field of medicine. The oral levetiracetam solution mainly contains levetiracetam, glucosyl-beta-cyclodextrin, a sweetening agent, a preservative, aromatic, buffer salt, a pH regulator and a solvent. Compared with oral solid preparations such as tablets in the market, the administration dosageof the oral levetiracetam solution can be flexibly adjusted, and different drug demands of patients can be met without purchase of multiple specifications of products. The oral levetiracetam solutionhas a good taste, can also fill the shortcoming of short supply of antiepileptic drugs for children in the market and meets the drug demands of children and patients difficult in swallowing. The preparation method of the oral levetiracetam solution comprises the steps that the glucosyl-beta-cyclodextrin and the levetiracetam form a clathrate compound, then the sweetening agent, the aromatic and an algefacient are added. T