Crystallization method of cephalosporins
Belonging to the field of industrial production technologies of beta-lactam antibiotics, the invention discloses a crystallization method of cephalosporins. The method is carried out in 2-4 crystallization kettles continuously. The method has the advantages of high continuation degree, simple operat...
Gespeichert in:
Hauptverfasser: | , , , , , , , , , , , , , , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Belonging to the field of industrial production technologies of beta-lactam antibiotics, the invention discloses a crystallization method of cephalosporins. The method is carried out in 2-4 crystallization kettles continuously. The method has the advantages of high continuation degree, simple operation and high production efficiency, and is suitable for large-scale industrialized production, improves equipment utilization rate and product yield, and the obtained cephalosporins finished product has an ideal short rod-like crystal form, and the crystals have the characteristics of good integrity, uniform granularity, high purity, good fluidity, and convenient separation, drying and packaging.
本发明公开了种头孢类抗生素的结晶方法,属于β内酰胺类抗生素的工业化生产工艺领域,在2~4个结晶釜中连续进行;本发明具有连续化程度高、操作简单、生产效率高、适合工业化大规模生产的优点,提高了设备利用率和产品收率,得到的头孢类抗生素成品具有理想的短棒状晶型,且晶体完整度好、粒度均匀、纯度高、流动性好、便于分离、干燥和分装。 |
---|