Preparation method of bagasse xylan gallate/oryzanol with antineoplastic activity

The invention discloses a preparation method of bagasse xylan gallate/oryzanol with antineoplastic activity. The preparation method comprises the following steps: using triacetyl nutgall acyl chloridegenerated through acetylation and acylating chlorination reactions of gallate as an esterifying agen...

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Hauptverfasser: QIAN JINGXIA, ZHANG SHUFEN, YANG SHIJUN, YANG YINGYING, LI HEPING, HUANG HONGXIA, SU NIANYING, SUN YAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a preparation method of bagasse xylan gallate/oryzanol with antineoplastic activity. The preparation method comprises the following steps: using triacetyl nutgall acyl chloridegenerated through acetylation and acylating chlorination reactions of gallate as an esterifying agent, and carrying out an esterification reaction with bagasse xylan in an N,N-dimethyl formamide organic solvent to synthesize bagasse xylan gallate; then selecting acylating chlorination ferulic acid with high biological activity as a second-step esterifying agent, using p-toluenesulfonic acid as acatalyst, carrying out a secondary esterification reaction with the bagasse xylan gallate in an acetone solvent, and further synthesizing the bagasse xylan gallate/oryzanol with antineoplastic activity. Suction filtration and washing are carried out on the product in a sodium bicarbonate absolute ethyl alcohol saturated solution, that is, the bagasse xylan double esterification derivative bagassexylan gallate/oryzanol with