Synthesis method for diaryl methanol compound

The technical solution and content of the invention relate to a synthesis method for a diaryl methanol compound shown as formula (I); the formula (I) is shown in the specification. The method includesthe following steps: under the existence of a palladium-sourced compound catalyst and organic phosph...

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Hauptverfasser: CHEN JIUXI, ZHEN QIANQIAN, HU KUN, SHAO YINLIN, XU TONG, YAO XINRONG, YE PENGQING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The technical solution and content of the invention relate to a synthesis method for a diaryl methanol compound shown as formula (I); the formula (I) is shown in the specification. The method includesthe following steps: under the existence of a palladium-sourced compound catalyst and organic phosphine ligand, in an organic solvent, an aldehyde derivative shown as formula (II) reacts with an organic cyclic triolborate compound shown as formula (III), and after the reaction is completed, post-processing is carried out, so that the diaryl methanol compound shown as formula (I) is obtained. According to the method, the reaction between the aldehyde compound and the organic cyclic triolborate compound can be smoothly carried out, so that the diaryl methanol compound can be obtained at high yield, a brand new synthesis route is provided for the synthesis of the compound, and a good application prospect and good industrial value are achieved. 本发明的技术方案和内容涉及种下式(I)所示二芳基甲醇类化合物的合成方法,所述方法包括:在钯源化合物催化剂和有机膦配体存在下,于有机溶剂中,上式(I