Rupatadine fumarate tablet and preparation method thereof
The invention discloses a rupatadine fumarate tablet and a preparation method thereof, and belongs to the technical field of medicines. Rupatadine fumarate, which serves as an active ingredient of themedicine (the tablet), is combined with pharmaceutical adjuvants, namely a filler, an adhesive and a...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a rupatadine fumarate tablet and a preparation method thereof, and belongs to the technical field of medicines. Rupatadine fumarate, which serves as an active ingredient of themedicine (the tablet), is combined with pharmaceutical adjuvants, namely a filler, an adhesive and a disintegrant, so that particles are prepared, and a lubricant is added to the particles, so that the tablets are prepared. Every 1000 tablets consist of 12.8g of rupatadine fumarate, 30-60g of lactose, 15-45g of microcrystalline cellulose, 3-20g of pre-gelatinized starch, 2-10g of low-substitutedhydroxypropyl cellulose, 0.03-0.3g of ferric oxide and 0.3-12g of a lubricant. The tablet prepared by the invention, by screening the varieties and dosages of the filler, the disintegrant, the adhesive and the lubricant and by adopting specific technological conditions such as screening meshes and the like on the raw materials in a preparing process, is stable in property, good in content uniformity, good in dissolution ra |
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