PROCESS FOR THE PREPARATION OF DOLUTEGRAVIR

Processes for the preparation of dolutegravir and pharmaceutically acceptable salts utilizing alkenylamine are disclosed. Intermediates in those synthetic schemes are also disclosed. 本发明公开了用烯基胺制备德罗格韦及其药学上可接受的盐的方法。还公开了这些合成方案中的中间体。...

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Hauptverfasser:	RAMABHOTLA REVATHI SRINIVAS, NADELLA MADUMURTHY, BHALME MITALI, ARUMALLA VENKATA SIVA REDDY, KILARU RAVEENDRA BABU, VELLANKI SIVARAM PRASAD
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	Processes for the preparation of dolutegravir and pharmaceutically acceptable salts utilizing alkenylamine are disclosed. Intermediates in those synthetic schemes are also disclosed. 本发明公开了用烯基胺制备德罗格韦及其药学上可接受的盐的方法。还公开了这些合成方案中的中间体。