Method for synthesizing aldehyde compounds based on WK (Willgerodt-Kindler) reaction and VHA (Vilsmeier-Haack-Arnold) reaction

The invention discloses a method for synthesizing aldehyde compounds based on WK (Willgerodt-Kindler) reaction and VHA (Vilsmeier-Haack-Arnold) reaction. The method includes the steps: taking acyl compounds as raw materials, and synthesizing carboxylic acid compounds through the WK (Willgerodt-Kindler) reaction; preparing Vilsmeier-Haack-Arnold reagents; adding the carboxylic acid compounds into the Vilsmeier-Haack-Arnold reagents to synthesize onium salt condensing agents; hydrolyzing the onium salt condensing agents to obtain the aldehyde compounds. The method is reasonable in synthetic route, stable and reliable and high in synthetic efficiency and has wide application prospects and high commercial values, the carboxylic acid compounds, the onium salt condensing agents and the aldehyde compounds can be simultaneously acquired, and types of inorganic and organic compounds and synthetic methods of inorganic and organic fields are enriched. 本发明公开了种基于Willgerodt-Kindler反应和Vilsmeier-Haack-Arnold反应合成醛类化合物的方法，包括以酰