Method for synthesizing N-(5-sucrose ester valeryl)mexiletine online by lipozyme catalysis

The invention discloses a method for synthesizing N-(5-sucrose ester valeryl)mexiletine online by lipozyme catalysis. The method takes N-(5-vinyl ester valeryl)mexiletine and sucrose as raw materials according to the amount of substance ratio of 1 to (1 to 10), dimethyl sulfoxide (DMSO) and tert-amyl alcohol as reaction solvents and lipozyme TL IM as a catalyst, and comprises the following steps: putting the raw materials and the reaction solvents into an injector; uniformly filling the lipozyme TL IM into a reaction channel of a micro-fluidic channel reactor; continuously introducing the raw materials and the reaction solvents into a reaction channel device under the pushing of the injector and carrying out esterification reaction, wherein the inner diameter of the reaction channel of the micro-fluidic channel reactor is 0.8mm to 2.4mm and the length of the reaction channel is 0.5m to 1.0m; controlling the reaction temperature to 20 DEG C to 60 DEG C and the reaction time to 20min to 40min; collecting a reac