TSLP binding proteins

The present disclosure relates to TSLP binding proteins, such as anti-TSLP single variable domains, polynucleotides encoding such TSLP binding proteins, pharmaceutical compositions and kits comprising said TSLP binding proteins and methods of manufacture. The present invention also concerns the use...

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Bibliographische Detailangaben
Hauptverfasser: DIMECH CAROLINE, SHAH RACHANA SHAILESH, MORLEY PETER, BARTHOLOMEW MICHELLE ANNE, AHMED FARHEEN, DELLA CRISTINA PIETRO, TILLING PAULA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The present disclosure relates to TSLP binding proteins, such as anti-TSLP single variable domains, polynucleotides encoding such TSLP binding proteins, pharmaceutical compositions and kits comprising said TSLP binding proteins and methods of manufacture. The present invention also concerns the use of such TSLP binding proteins in the treatment of diseases associated TSLP signalling, such as asthma. 本发明涉及TSLP结合蛋白,如抗TSLP单可变域,编码该TSLP结合蛋白的多核苷酸,包含所述TSLP结合蛋白的药物组合物和试剂盒和制备方法。本发明还涉及该TSLP结合蛋白治疗与TSLP信号传递相关的疾病,如哮喘的用途。