Cd38 inhibitors and methods of treatment
Compounds of Formula (I) and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed. Formula (I). 本发明公开了式I的化合物，以及通过抑制CD38酶来调节细胞NAD+水平，从而治疗代谢疾病的方法。式I。...
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| creator | HENKE BRAD RICHARD CADILLA RODOLFO HAFFNER CURT BECHERER J DAVID DEATON DAVID NORMAN SCHULTE CHRISTIE PREUGSCHAT FRANK |
| description | Compounds of Formula (I) and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed. Formula (I).
本发明公开了式I的化合物，以及通过抑制CD38酶来调节细胞NAD+水平，从而治疗代谢疾病的方法。式I。 |
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本发明公开了式I的化合物，以及通过抑制CD38酶来调节细胞NAD+水平，从而治疗代谢疾病的方法。式I。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2017</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171201&DB=EPODOC&CC=CN&NR=107428733A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20171201&DB=EPODOC&CC=CN&NR=107428733A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HENKE BRAD RICHARD</creatorcontrib><creatorcontrib>CADILLA RODOLFO</creatorcontrib><creatorcontrib>HAFFNER CURT</creatorcontrib><creatorcontrib>BECHERER J DAVID</creatorcontrib><creatorcontrib>DEATON DAVID NORMAN</creatorcontrib><creatorcontrib>SCHULTE CHRISTIE</creatorcontrib><creatorcontrib>PREUGSCHAT FRANK</creatorcontrib><title>Cd38 inhibitors and methods of treatment</title><description>Compounds of Formula (I) and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed. Formula (I).
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本发明公开了式I的化合物，以及通过抑制CD38酶来调节细胞NAD+水平，从而治疗代谢疾病的方法。式I。</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Cd38 inhibitors and methods of treatment |
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