Application of composition containing fructose-1,6-bisphosphate in preparation of antitumor drugs

The invention provides application of a composition containing fructose-1,6-bisphosphate (FBP) in preparation of antitumor drugs. A proportion of the FBP to metabolic regulators are determined according to respective efficacy doses; the metabolic regulators are different in doses, so that the propor...

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Bibliographische Detailangaben
Hauptverfasser: BI HONGYUN, LIAN XIAOYUAN, ZHANG ZHIZHEN, HU YUHUAI, QIAN HENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides application of a composition containing fructose-1,6-bisphosphate (FBP) in preparation of antitumor drugs. A proportion of the FBP to metabolic regulators are determined according to respective efficacy doses; the metabolic regulators are different in doses, so that the proportion of the FBP to one metabolic regulator is determined according to the effective dose of the specific metabolic regulator. The composition prevents and cures tumors by damaging activity of a tumor metabolic network. The drugs with the composition as an active ingredient have stronger anticancer efficacy compared with FBP and other metabolic regulators in exclusive use. The composition can completely reverse tumor metabolic characteristics and destroy the tumor metabolic network, prominently featured by blocking glycolysis and an intermediate product of a tricarboxylic acid cycle from biosynthesis while promoting nutriments to enter the tricarboxylic acid cycle and oxidative phosphorylation so as to damage an oxi