Medical application of fructose-1, 6-diphosphonic acid and its blood concentration stabilizer composition

The invention provides a medical application of fructose-1, 6-diphosphonic acid and its blood concentration stabilizer composition, and relates to an application of preparing drugs to prevent and treat metabolic disease and metabolic mal-function related diseases. The medical form of the FBP comprises fructose-1, 6-diphosphonic acid primary form and fructose-1, 6-diphosphonic acid, and pharmaceutically acceptable salt and hydrate of its prodrug or derivative. The blood concentration stabilizer composition refers to a drug or a matter capable of slowing down the rapid degradation of FBP in the drug preparation in the body and treating the diabetes. The blood concentration stabilizer composition can generate high FBP blood concentration peak value and more stable blood concentration and more significant drug effect, reduce FBP dosage and decrease toxicity for a large number of inorganic phosphorus enter a human body circulation after the hydrolysis of large dose of FBP; through different FBP function mechanisms