A method for preparing metal organogel used for loading a medicine

The invention relates to a method for preparing metal organogel released in vitro and used for loading a medicine, and particularly a method for preparing metal organogel used for loading methyl salicylate. The main objective of the invention is to overcome a problem that medicine spraying agents ar...

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Hauptverfasser: ZHANG FENGMING, MENG XIANGBIN, DONG HONG, WANG XUELIANG, GUO CHENGQUAN, SHENG JINGLI, ZHANG XIN, YANG DOUDOU, SUN XIAOJUN, WANG JIANHUI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a method for preparing metal organogel released in vitro and used for loading a medicine, and particularly a method for preparing metal organogel used for loading methyl salicylate. The main objective of the invention is to overcome a problem that medicine spraying agents are released excessively fast and liable to volatize. The method includes 1) dissolving AlCl .6H2O and L-tartaric acid into an absolute ethanol solvent, then adding the methyl salicylate into the solution, performing ultrasonic treatment until solid is completely dissolved, and pouring an obtained mixed solution into a glass bottle, and 2) putting the glass bottle in the step 1) into polytetrafluoroethylene, performing a constant-temperature reaction at 120 DEG C for 48 h, and naturally cooling a product to room temperature to obtain the metal organogel used for loading the medicine. The loading amount of the organogel can be 55% and the release time can be as long as 10 h. 种用于载药的体外释放的金属有机凝胶的制备方法。本发明涉及了种用于负载水杨酸甲酯的金属有