Preparation method of magnetically targeted nano INH/HBPE-DDSA/Fe O composite drug carrying microspheres

The invention relates to a preparation method of magnetically targeted nano isoniazid (INH)/functionalized hyperbranched polyester (HBPE-DDSA)/ferrosoferric oxide (INH/HBPE-DDSA/Fe O ) composite drug carrying microspheres for tuberculosis treatment, belongs to the technical field of medicine, and relates to a nanocomposite material. The preparation method of the nano INH/HBPE-DDSA/Fe O drug carrying microspheres comprises the steps that by means of a process intensification method, in the conditions of vacuumization and ultrasonic radiation, INH and HBPE-DDSA are added while Fe O is prepared, and the nano INH/HBPE-DDSA/Fe O drug carrying microspheres are preparedin a one-stage process. The preparation method is characterized in that one-stage process is adopted, and intensified reaction processes of the vacuumization and the ultrasonic radiation are introduced. The preparation method has the advantages that the process is simple and controllable; the nano INH/HBPE-DDSA/Fe O drug carrying microspheres prepared