Recombinant long-acting interferon for sheep as well as fusion proteins for preparing long-acting interferon and preparation method of fusion proteins

The invention discloses recombinant long-acting interferon for sheep as well as fusion proteins for preparing the long-acting interferon and a preparation method of the fusion proteins. The fusion proteins are prepared from interleukin 2 of the sheep and interferon tau of the sheep through flexible linker bonding; the fusion proteins are blended with a lyophilization protecting agent to obtain a mixture, and then the mixture is freeze-dried to obtain the recombinant long-acting interferon for the sheep. According to the recombinant long-acting interferon for the sheep, the half-life period of the interferon for the sheep can be obviously prolonged; compared with the half-life period of common interferon for the sheep, the half-life period of the interferon for the sheep disclosed by the invention is increased by 8 times or more, and the recombinant long-acting interferon has a broad spectrum antiviral effect and can improve the immune response of the sheep. 本发明公开了种重组羊长效干扰素及制备此长效干扰素的融合蛋白及其制备方法，所述融合蛋白由羊白细胞介素2与羊